Marfan's Syndrome

Are you excessively tall? Do you have long bones“His fingers are long and slender (spider
that aren’t proportionate to the rest of yourfingers). Weakness of ligaments, tendons and joint
body? Perhaps you have Marfan’s syndrome.capsules results in joints that are loose,
Marfan's syndrome (arachnodactyly) is a rarehyperextensible, and habitually dislocated.
inherited disorder of connective tissue that causesExcessive growth of the rib bones give rise to
defects in the eyes, skeleton and cardiovascularchest deformities," she added.
system. It affects both males and females andOther symptoms are pectus excavatum (funnel
may occur any time from early infancy tobreast), frequent hernia and scoliosis (the
adulthood.sideways curvature of the spine). Death from
The symptoms of Marfan's syndrome developMarfan's syndrome is often due to cardiovascular
gradually over the years. These include longcomplications.
slender bones which make a person excessivelyIn severe cases, the elastic fibers in the media
tall, long slender fingers and toes, heart defects(middle layer) of the aorta (the main artery of
and a partial dislocation of the lenses of the eyes.the body) may be damaged, leading to aneurysm
"The most common signs of this disease are(a ballonlike swelling).
skeletal abnormalities particularly excessively longThere is no specific test for Marfan's syndrome
tubular bones and an arm span exceeding theand the diagnosis is made mainly on its
patient's height. Usually the patient is taller thansymptoms. Treatment is aimed at relieving
average for his family, with the upper half of hissymptoms and preventing complications. These
body shorter than average and the lower half,include surgery to repair aneurysm, eye defects
longer,” according to Helen L. Davis of theand spinal curvature, and hormone therapy to
Thomas Jefferson University Hospital, Philadelphiastop the patient from growing abnormally tall.
in “Diseases.”