| Long QT syndrome (LQTS) is a disorder of the | | | | the end of the T wave. People who have LQTS |
| heart's electrical system. People with this | | | | are at risk for syncope and sudden death, often |
| syndrome are susceptible to an abnormally rapid | | | | at a young age. |
| heart rhythm called "Torsade des pointes." Long | | | | Causes of Long QT syndrome |
| QT syndrome is characterized by a prolongation | | | | The common causes and risk factor's of Long QT |
| of the QT interval on ECG and a propensity to | | | | syndrome include the following: |
| ventricular tachyarrhythmias, which may lead to | | | | LQTS can be caused by certain medicines, or it |
| syncope, cardiac arrest, or sudden death. LQTS is | | | | can be the result of a stroke or some other |
| usually inherited as an autosomal dominant trait. In | | | | neurologic disorder. |
| the case of LQT1, which has been mapped to | | | | Heart medications. |
| chromosome 11, mutations lead to serious | | | | Lipid-lowering medications. |
| structural defects in the person's cardiac | | | | Psychotropic medications. |
| potassium channels that do not allow proper | | | | Blood relatives of family members with LQTS. |
| transmission of the electrical impulses throughout | | | | You also have an increased risk for LQTS if other |
| the heart. It is associated with syncope (loss of | | | | members of your family have the disorder. |
| consciousness) and with sudden death due to | | | | Symptoms of Long QT syndrome |
| ventricular arrhythmias. In the long Q-T | | | | Some sign and symptoms related to Long QT |
| syndrome, the above-described Q-T interval is | | | | syndrome are as follows: |
| prolonged. Arrhythmias in individuals with LQTS | | | | Abnormal heart rhythms. |
| are often associated with exercise or excitement. | | | | Seizures. |
| The cause of sudden cardiac death in individuals | | | | Sudden shortness of breath. |
| with LQTS is ventricular fibrillation. Congenital | | | | Fainting: In people with long QT syndrome, fainting |
| LQTS is a rare disorder that is usually inherited | | | | spells (syncope) are caused by the heart |
| (passed down through family members). | | | | temporarily beating in an erratic way. |
| It usually affects children or young adults. In other | | | | Sudden death. |
| cases, LQTS can be caused by certain medicines, | | | | Sudden chest pain. |
| or it can be the result of a stroke or some other | | | | In one type of inherited long Q-T syndrome, the |
| neurologic disorder. LQTS can lead to an abnormal | | | | person is also deaf. |
| heart rhythm (arrhythmia); fainting or loss of | | | | Treatment of Long QT syndrome |
| consciousness (syncope); or even sudden death. | | | | The common causes and risk factor's of Long QT |
| Long QT syndrome may explain some rare | | | | syndrome include the following: |
| instances of sudden death in young people where | | | | There are treatments for long Q-T syndrome, |
| no obvious cardiac heart abnormality is found. | | | | including medications such as beta blockers. |
| People with this syndrome may show prolongation | | | | Some people may benefit from an implantable |
| of the Q-T interval during physical exercise, | | | | defibrillator. |
| intense emotion (such as fright, anger or pain), or | | | | Propranolol and nadolol are the beta-blockers most |
| by a startling noise. In LQTS, QT prolongation can | | | | frequently used, though atenolol and metoprolol |
| lead to polymorphic ventricular tachycardia, or | | | | are also prescribed in patients with LQTS. |
| torsade de pointes, which itself may lead to | | | | When LQTS causes uncontrolled ventricular |
| ventricular fibrillation and sudden cardiac death. | | | | fibrillation, you might need an implantable |
| Individuals with LQTS have a prolongation of the | | | | cardioverter defibrillator (ICD). An ICD is a device |
| QT interval on the ECG. The Q wave on the ECG | | | | that sends an electric shock to your heart to |
| corresponds to ventricular depolarization while the | | | | restore a normal heartbeat. |
| T wave corresponds to ventricular repolarization. | | | | For many people with LQTS, the implantable |
| The QT interval is measured from the Q point to | | | | defibrillator is the best treatment. |