| Erythema annulare centrifugum (EAC) is classified | | | | terminal stage of the disease. |
| as one of the figurate or gyrate erythemas. A | | | | Erythema annulare centrifugum usually clears up |
| large number of other descriptive terms have | | | | by itself. Topical corticosteroids may be helpful in |
| been used to classify these types of lesions, | | | | reducing redness, swelling and itchiness. Systemic |
| some of which include annular erythema. | | | | or injection steroid therapy is effective treatment. |
| Hypotheses about the mechanism of annularity | | | | Most cases require no treatment, however topical |
| focus on the interaction between mediators of | | | | corticosteroids may be helpful in reducing redness, |
| inflammation and ground substance as foreign | | | | swelling and itchiness. Systemic or injection steroid |
| antigens diffuse through the skin. EAC is | | | | therapy is effective, but the eruption returns |
| considered to include all the gyrate erythemas, | | | | once these drugs are withdrawn. EAC is a chronic |
| except for erythema marginatum rheumaticum, | | | | and recurrent disease despite treatment. EAC is |
| erythema chronicum migrans, and erythema | | | | thought to be highly associated with internal |
| gyratum repens. Eruptions may occur at any time | | | | disease as well as with superificial fungal infection. |
| throughout life, from infancy to old age. EAC has | | | | Drugs including chloroquine and |
| been reported in patients from infancy to the | | | | hydroxychloroquine, oestrogen, penicillin and |
| ninth decade of life. | | | | amitriptyline. Bacterial, fungal and viral infections |
| Lesions most often appear on the thighs and legs, | | | | such as tuberculosis, sinusitis, candidiasis or tinea |
| but may occur on the face, trunk and arms. EAC | | | | Erythema Annulare Centrifugum - Prevention and |
| may precede malignancy by 2 years or more. It | | | | Treatment Tips |
| has been noted that erythema annulare | | | | 1. Topical corticosteroids may be helpful in |
| centrifugum is sometimes linked to underlying | | | | reducing redness, swelling and itchiness. |
| diseases and conditions. Cause of erythema | | | | 2. Systemic or injection steroid therapy is |
| annulare centrifugum bacterial, fungal and viral | | | | effective treatment. |
| infections such as tuberculosis, sinusitis, candidiasis | | | | 3. Systemic or injection steroid therapy is |
| or tinea , drugs including chloroquine and | | | | effective. |
| hydroxychloroquine, oestrogen, penicillin and | | | | 4. Many Drugs including chloroquine and |
| amitriptyline ,cancer ,food, most often blue | | | | hydroxychloroquine is effective treatment for |
| cheese or tomatoes ,recurrent or chronic | | | | erythema annulare centrifugum. |
| appendicitis ,cholestatic liver disease (blocked bile | | | | 5. Other drugs oestrogen, , penicillin and |
| system) and grave's disease. EAC cleared in the | | | | amitriptyline reduce lesion. |