Botulism – Causes, Symptoms, Prevention, Diagnosis and Treatment

A bacterium that occurs widely in nature and is a· foodborne botulism
cause of botulism; it has six main types, A to F.· infant botulism
Botulism is a rare but potentially very serious· wound botulism
illness. The bacterium may be entered the bodyDiagnosis
through wounds.Physicians may consider the diagnosis if the
A severe, manytimes fatal food poisoning causedpatient's history and physical examination suggest
by ingestion of food containing botulin. It may bebotulism. However, these clues are often not
characterized by nausea, vomiting, disturbedenough to allow a diagnosis of botulism. Other
vision, muscular weakness, and fatigue.diseases such as Guillain-Barré syndrome,
How is Botulism Transmitted?stroke, and myasthenia gravis can appear similar
Cases of foodborne botulism often come fromto botulism, and special tests may be needed to
home-canned foods with low acid content, suchexclude these other conditions. These tests may
as asparagus, green beans, beets, and corn.include a brain scan, cerebrospinal fluid
Clostridium botulinum bacteria is anaerobic, whichexamination, nerve conduction test
means it can survive and grow with little or no(electromyography, or EMG), and an Edrophonium
oxygen. Therefore, it can survive very well inChloride (Tensilon) test for myasthenia gravis.
sealed containers. Outbreaks of the botulism arePrevention
often from more unusual sources such as chiliLike many germs, the bacteria that cause
peppers, tomatoes, and improperly handled bakedbotulism in infants are everywhere in the
potatoes wrapped in aluminum foil.environment. They're in dust and dirt. They're
Causeseven in the air. Experts don't know why some
Clostridium botulinum is a spore-forming organisminfants end up consuming the airborne bacteria
that is common in nature. The spores may beand contracting botulism while others don't.
found in soil and certain foods (such as honey andTreatment
some corn syrups). Infant botulism occurs mostlyThe symptoms of botulism make hospitalization
in young infants between 6 weeks and 6 monthsnecessary. If diagnosed early, botulism can be
of age. It has been reported to occur as early astreated with an antitoxin, which blocks the action
6 days and as late as 1 year. Risk factors includeof the toxin circulating in the blood. This can
swallowing honey as a baby, being aroundprevent patients from worsening, but recovery
contaminated soil, and having less than one stoolstill takes many weeks. If left untreated, a patient
per day for a period greater than 2 months.may need to be on a breathing machine
Symptoms of Botulism(ventilator) for weeks and would require intensive
According to the CDC, initial symptoms ofmedical and nursing care. Infant botulism is treated
Botulism include:with immune globulin, which is similar to the
Double vision, slurred speech, difficulty swallowing,antitoxin. Most cases of botulism recover with
and muscle weakness. In the food-borne version,appropriate medical care. The goal of botulism
symptoms usually appear within a day or two oftreatment is to establish a clear airway, aid
consuming the contaminated food.breathing, give botulinus anti-toxin, and provide
There are three main types of botulism:supportive therapy.